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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR5A2
All Species:
36.67
Human Site:
Y489
Identified Species:
62.05
UniProt:
O00482
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00482
NP_003813.1
541
61331
Y489
L
D
Y
T
M
C
N
Y
P
Q
Q
T
E
K
F
Chimpanzee
Pan troglodytes
XP_520248
771
84677
Y719
L
D
Y
T
L
C
H
Y
P
H
C
G
D
K
F
Rhesus Macaque
Macaca mulatta
XP_001110281
541
61327
Y489
L
D
Y
T
M
C
N
Y
P
Q
Q
T
E
K
F
Dog
Lupus familis
XP_547371
548
62005
Y496
L
D
Y
T
M
C
N
Y
P
Q
Q
T
E
K
F
Cat
Felis silvestris
Mouse
Mus musculus
P45448
560
64002
Y508
L
D
Y
T
V
C
N
Y
P
Q
Q
T
E
K
F
Rat
Rattus norvegicus
Q9QWM1
560
63886
Y508
L
D
Y
T
L
C
N
Y
P
Q
Q
T
E
K
F
Wallaby
Macropus eugenll
Q95L87
463
51850
F418
Y
P
H
C
G
D
K
F
R
Q
L
L
L
R
L
Platypus
Ornith. anatinus
XP_001505652
637
72367
Y585
L
D
Y
I
M
C
N
Y
P
Q
Q
T
D
K
F
Chicken
Gallus gallus
O42101
501
57084
Y449
L
D
Y
T
M
C
N
Y
P
Q
Q
T
D
K
F
Frog
Xenopus laevis
P70033
435
49986
R391
R
Y
P
H
Q
P
N
R
F
P
D
L
M
M
C
Zebra Danio
Brachydanio rerio
Q9PU65
477
54037
G433
P
E
I
R
C
I
A
G
K
L
V
N
I
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P33244
1027
108400
Y974
L
D
Y
T
L
T
C
Y
P
S
V
N
D
K
F
Honey Bee
Apis mellifera
XP_001122182
878
92065
Y826
L
D
Y
T
L
T
C
Y
P
S
I
P
D
K
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791919
487
54933
F442
Y
T
N
V
S
D
K
F
R
L
M
L
R
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
99.6
88.1
N.A.
86.9
86.9
57.4
80.6
90
23.6
27.5
N.A.
26.1
28.2
N.A.
45.4
Protein Similarity:
100
52.1
99.8
89.7
N.A.
90.3
90.5
67.8
83
91.1
41.2
44.7
N.A.
35.8
40.2
N.A.
61
P-Site Identity:
100
60
100
100
N.A.
93.3
93.3
6.6
86.6
93.3
6.6
0
N.A.
53.3
53.3
N.A.
0
P-Site Similarity:
100
80
100
100
N.A.
100
100
26.6
93.3
100
6.6
6.6
N.A.
66.6
66.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
8
58
15
0
0
0
8
0
0
0
8
% C
% Asp:
0
72
0
0
0
15
0
0
0
0
8
0
36
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
36
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
8
0
0
0
0
0
72
% F
% Gly:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% G
% His:
0
0
8
8
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
8
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
15
0
8
0
0
0
0
72
0
% K
% Leu:
72
0
0
0
29
0
0
0
0
15
8
22
8
8
22
% L
% Met:
0
0
0
0
36
0
0
0
0
0
8
0
8
8
0
% M
% Asn:
0
0
8
0
0
0
58
0
0
0
0
15
0
0
0
% N
% Pro:
8
8
8
0
0
8
0
0
72
8
0
8
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
58
50
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
8
15
0
0
0
8
8
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
15
0
0
0
0
0
% S
% Thr:
0
8
0
65
0
15
0
0
0
0
0
50
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
8
72
0
0
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _